Endocrine Abstracts

Objective: The aim of this meta-analysis is to evaluate the effect of bariatric surgery on sexual function and sex hormone levels in obese patients.Methods: Two independent investigators conducted a literature search of PubMed, Medline and Cochrane databases using the terms bariatric surgery, sexual function and sex hormone to identify appropriate human studies published in English about the effect of bariatric surgery on sexua...

Objectives: Overweight and obesity currently burden our public health, and especially with the aging process in the world, the incidence of obesity is significantly higher in women than that in men partly. Recent studies reported that hypothalamic kisspeptin neurons, with obvious changes of number and structure in female during life, play a crucial role in the regulation of central energy homeostasis. But the precise mechanism remains an enigma.Methods: ...

Objectives: This study aims to determine which metabolic tissue is involved in the process of kisspeptin neurons regulate energy metabolism so that it may provide a novel therapy for metabolic related diseases such as obesity.Methods: Kiss1-CreGFP mice were used in this study. And we selectively activated kisspeptin neurons by using Designer-receptors-exclusively-activated-by-designer-drugs (DREADDs) technology. Mice were bilaterally injected with the Cr...